After leaving Washington, Burr traveled west seeking new opportunities, both economic and political. His activities eventually led to his arrest on charges of treason in 1807. Although the subsequent trial resulted in acquittal, Burr's western schemes left him with large debts.
Most of his few influential friends had dropped him. In a final bid for grand opportunities, he left the United States for Europe. He remained overseas until 1812, when he returned to the United States to practice law in New York City..